Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase
Reexamination Certificate
2005-07-19
2009-06-16
Saidha, Tekchand (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving oxidoreductase
C435S189000
Reexamination Certificate
active
07547524
ABSTRACT:
The present invention relates to improved variants of soluble pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenases (s-GDH) comprising an amino acid insertion between positions 428 and 429 as corresponding to the amino acid sequence known fromAcinetobacter calcoaceticus, to genes encoding such variant s-GDH, to proteins of such s-GDH variants with improved substrate specificity for glucose, and to different applications of these s-GDH variants, particularly for determining concentrations of sugars, especially of glucose in a sample.
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Boenitz-Dulat Mara
Knappe Wolfgang-Reinhold
Kratzsch Peter
Laggerbauer Jessica
Schmuck Rainer
Barnes & Thornburg LLP
Roche Diagnostics Operations Inc.
Saidha Tekchand
LandOfFree
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