Genetically engineered human acetylcholinesterase

Details Genetically engineered human acetylcholinesterase Genetically engineered human acetylcholinesterase

1993-08-02

1997-01-21

Wax, Robert A.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435197, 4353701, 4352523, 536 232, 536 235, C12N 500, C12N 1500, C12N 918

Patent

active

055959032

ABSTRACT:
Genetically engineered human acetylcholinesterase and antibodies that def the protein are described. These composition may be used in pharmaceutical preparations for treatment and prophylaxis of organo-phosphorous compound poisoning or post-operative apnea. Also described are human cholinesterase DNA probes which may be employed for diagnosing progressing ovarian carcinomas and hemocytopoietic disorders.

REFERENCES:
patent: 5248604 (1993-09-01), Fischer
Weitz et al., Biochim et Biopys Acta, 776:56-74, 1984.
Prody et al, PNAS, vol. 84 3555-3559, Jun. 1987.
Shumacher et al., Nature, vol. 319:405-409, Jan. 30, 1986.
Young et al, PNAS, vol. 80, Mar., 1983, pp. 1194-1198.

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