Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Patent
1996-09-11
2000-03-21
Fox, David T.
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
4353201, 536 236, 536 241, 800278, C12N 1529, C12N 1582
Patent
active
060401850
ABSTRACT:
Disclosed is a stabilized gene for transforming a host plant cell said gene comprising a gene exogenous to the plant cell and at least one stabilizing DNA segment in a 3'- or 5'-flanking region to said exogenous gene. Additionally, the invention relates to vectors comprising at least one stabilizing DNA segment in a 3'- or 5'-flanking region to the exogenous gene and methods for transforming plant cells. These stabilizing DNA segments include MAR, SAR, LCR, or LAR, HR and other repetitive elements.
REFERENCES:
patent: 5187267 (1993-02-01), Comai et al.
Stoilov, L.M. et al., (1992), Plant Cell Reports, 11:355-358.
Hudspeth, R.L. and J.W. Grula, (1989), Plant Molecular Biology, 12:579-589.
Bowen. Brian C., (1981), Nucleic Acids Research, 9:(19):5093-5108.
DeBlock, M. et al., (1984), EMBO Journal, 3 (8) 1681-1689.
Gasser, S.M., (1988) Architecture of Eukaryotic Genes: Symposium on Chromatin Structure of Plant Genes, Frankfurt am Main, W. Germany, Sep., 1986, XIV t 518, P. VCH Publishers, N.Y. pp. 461-471.
Phi-Van, L. et al., (1990), Mol. Cell. Biol., 10:2302-2307.
Eissenberg, J.C. and Elgen, S.C.R. (1991) Trends in Genetics, 7:335-340.
Hall, G. et al., (1991), Proc. Nat. Acad. Sci. USA 88:9320-9324.
Slatter. R.E., et al., (1991) Plant Cell,, 3:1239-1250.
Breyre, P. et al., (1992) Plant Cell, 4:463-471.
van Driel, R. et al., (1991), J. Cell. Biochem., 47:1-6.
Schoffl, F. et al., (1991), 3rd Intl. Cong. Soc. of Plant. Mol. Biol., Poster Abstract No. 407.
Schoffl, F. et al., (1993), Transgeneic Research, 2:93-100.
Childs, L.C., et al., (1992), Biological Abstracts/RRM, No. BR 44:6469.
Schoffl, F. et al., (1993), Chemical Abst. 118:(23) Abstract No. 227377.
Kleim, M. et al., (1991), Biological Absts., BR42:28037.
Ott, R.W. et al., (1990), Mol. Gen. Genet. 221: 121-124.
Mlynarova, L. et al., (1994), Plant Cell, 6:417-426.
Meyer. P. et al. (1988), Proc. Natl. Acad. Sci., USA, 85:8568-8572.
Marchesi, M.L. et al., (1989), Theor. Appl. Genet. 78:113-118.
Childs, L.C. et al., (1993), Biochem Gentics, 118:301.
Zabel, P. et al., (1986), Chem. Abst. vol. 104, No. 9, No. 63286.
Stief, Aribert et al., "A nuclear DNA attachment element mediates elevated and position-independent gene activity" Nature 341 (343-345) 1989.
Elgin, S.C.R. "Chromatin structure and gene activity" Current Opinion, Cell Biology 2 (437-445) 1990.
de Haas Johannes Maria
Dietrich Paul S.
Gielen Johannes Jacobus Ludgerus
Van Driel Roeland
Van Grinsven Martinus Quirinus Joseph Marie
Fox David T.
Hoxie Tom
Novartis AG
LandOfFree
Genetic stabilizing elements does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Genetic stabilizing elements, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Genetic stabilizing elements will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-729794