Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-12-25
2007-12-25
Spector, Lorraine (Department: 1647)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023500, C536S024100, C435S320100, C435S325000
Reexamination Certificate
active
09346470
ABSTRACT:
The present invention provides isolated nucleic acid molecules encoding polypeptides comprising functional steroid hormone and juvenile hormone receptors, in particular isolated nucleic acid molecules which encode polypeptides comprising theLucilia cuprinaandMyzus persicaeecdysone receptors and juvenile hormone receptors. The present invention further provides functional recombinant steroid and juvenile hormone receptors and recombinant polypeptide subunits thereof and derivatives and analogues thereof. The present invention further provides screening systems and methods of identifying insecticidally-active agents which are capable of agonizing or antagonizing insect receptor function, or alternatively or in addition, which modify the affinity of said receptors for their cellular stimuli (eg. insect steroids or juvenile hormones) or analogues thereof, or alternatively or in addition, which act as insecticides by virtue of their ability to agonize or antagonize the activity of insect hormones.
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Hannan Garry Noel
Hill Ronald Johnston
Commonwealth Scientific and Industrial Research Organisation
Greenlee Winner and Sullivan PC
Shafer Shulamith H.
Spector Lorraine
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