Genetic remodeling in Bifidobacterium

Details Genetic remodeling in Bifidobacterium Genetic remodeling in Bifidobacterium

2007-08-17

2011-12-06

Navarro, Albert (Department: 1645)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

C435S245000, C435S252100

Reexamination Certificate

active

08071353

ABSTRACT:
ABifidobacteriumcomprising a genome that is customized so as to lack an operable functional gene is disclosed. A method of making such cells is also disclosed. The method is used to makeBifidobacteriumcells that lack certain functional antibiotic resistance genes, such as tetW, and are sensitive to antibiotics such as tetracycline.

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