Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1994-05-25
1997-10-07
Elliott, George C.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4352401, 4352402, 43524023, 435240243, 435240241, 424 932, 424 9321, 600 36, 623 1, C12N 1586, C12N 516, A61F 204, A61F 206
Patent
active
056747225
ABSTRACT:
Endothelial cells transduced with genetic material encoding a polypeptide or protein of interest and, optionally, a selectable marker, as well as methods for making and using the transduced endothelial cells are disclosed. Such endothelial cells are useful in improving the performance of vascular grafts and in delivering the encoded polypeptide or protein, such as an enzyme, a hormone, a receptor or a drug, to an individual.
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Birinyi Louis K.
Callow Allan D.
Cohen Lawrence K.
Mulligan Richard C.
Rafield Lori F.
Brigham & Women's Hospital
Elliott George C.
Halluin Albert P.
Howard Hughes Medical Institute
New England Medical Center Hospitals
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