Genetic markers of food allergy

Details Genetic markers of food allergy Genetic markers of food allergy

2004-08-05

2010-06-08

Switzer, Juliet C (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200

Reexamination Certificate

active

07732135

ABSTRACT:
A genetic marker of food allergy is disclosed. The marker comprises variants of IL-4 receptor alpha, IL13 and CD14.

REFERENCES:
patent: WO 00/34789 (2000-06-01), None
Howell et al. (Clinical and Experimental Allergy, 1998, vol. 28, pp. 156-162).
Assa'ad et al.,Analysis of the R130Q IL-13 Polymorphism in Patients with Food Allergy, Pediatric Research, 2001; 49 (4-2):11A (XP008040169).
Liu et al.,Associations between total serum IgE levels and the 6 potentially functional variants within the genes IL4, IL13, and IL4Rα in German children: The German Multicenter Atopy Study, J Allergy Clin Immunol 2003; 112:382-388.
Mitsuyasu et al.,IIe50Val variant of IL4Rα upregulates IgE synthesis and associates with atopic asthma, Nature Genetics 1998; 19:119-120.
PCT,International Search Report, PCT/US2004/025370, mailed Jan. 7, 2005, 7 pg.
Risma Ka et al.,V75R576 IL-4 Receptor α Is Associated with Allergic Asthma and Enhanced II-4 Receptor Function, J Immunol. 2002; 169:1604-1610.
Woo JG et al.,-159 C to T Polymorphism of CD14 is Associated with Non-Atopic Asthma and Food Allergy, J Allergy Clin Immunol 2003; 111(2) Abstract Supplement:S127 (XP008040172).
Woo JG et al.,The -159 C->T polymorphism of CD14 is associated with nonatopic asthma and food allergy, J Allergy Clin Immunol 2003. 112:438-444.

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