Genetic markers for pig backfat thickness

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C536S024300, C435S091200

Reexamination Certificate

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07435543

ABSTRACT:
The present invention provides a method of screening pigs to identify those which have a genetic predisposition to have a thinner or thicker backfat thickness by assaying the pattern of the five single nucleotide polymorphisms in the HSP70.2 gene that is associated with backfat thickness.

REFERENCES:
Maak et al. 1998. Animal Genetics 29 (Suppl. 1) 60-74.
Maak et al. 1999. Arch. Tierz., Dummerstorf 42(1999) Special Issue, 141-143.
Roan, et al., “A Survey on the Antibiotic Residues in Pork in the Middle Part of Taiwan,” Journal of Chin. Soc. Anim. Sci. (1980), pp. 55-69 (1-2).
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Welch, William J., “Mammalian Stress Response: Cell Physiology, Structure/Function of Stress Proteins, and Implications for Medicine and Disease,” Physiological Review (1992), pp. 1063-1081, vol. 72, No. 4.
Schwerin, et al., “The Inducible Stress Protein 70.2 Gene—A Candidate Gene for Stress Susceptibility in Swine,” Arch. Animal Breed. (1999), pp. 61-66, vol. 42.
Huang, et al., “Association of Heat Shock Protein 70 with Semen Quality in Boars,” Animal Reproduction Science (2000), pp. 231-240, vol. 63.
Peelman, Luc J., et al., “Complete nucleotide sequence of a porcine HSP70 gene,” Immunogenetics, (1992) pp. 286-289, vol. 35, No. 4.
Maak, et al., Animal Genetics (1998) 29 (Suppl. 1) 60-74.
Maak, et al., Arch. Tierz., Dummerstorf 42 (1999) Special Issue, pp. 141-143.
Chen M. Y., et al., “Polymorphism in the 5′-flanking region of porcine heat shock protein 70.2 gene,” Animal Genetics (2000) pp. 404-419, vol. 31.
Ulbrecht et al. , Asociation of B2-Adrenoreceptor Variants with Bronchial Hyperresponsiveness, American Journal of Respiratory and Critical Care Medicine, vol. 161, pp. 469-474 (2000).
GenBank Accession AF139178, GI: 5031272, Sus scrofa heat shock protein 70.2 gene, promoter and partial cds. Jul. 3, 2001.

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