Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1994-11-17
1999-01-19
Low, Christopher S. F.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
43524021, 4352523, 43525233, 4351723, 4353201, 536 231, 536 235, 536 232, 536 241, 935 10, 935 29, 935 32, 935 70, 800 2, C12N 500
Patent
active
058612998
ABSTRACT:
Proteinaceous products can be produced by transgenic animals having genetic constructs integrated into their genome. The construct comprises a 5'-flanking sequence from a mammalian milk protein gene (such as beta-lactoglobulin) and DNA coding for a heterologous protein other than the milk protein (for example a serin protease such as alpha.sub.1 -antitrypsin or a blood factor such as Factor VIII or IX). The protein-coding DNA comprises at least one, but not all, of the introns naturally occurring in a gene coding for the heterologous protein. The 5'-flanking sequence is sufficient to drive expression of the heterologous protein.
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Archibald Alan Langskill
Clark Anthony John
Harris Stephen
McClenaghan Margaret
Simons Jonathan Paul
Low Christopher S. F.
PPL Therapeutics (Scotland) Limited
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