Genes which influence Pichia proteolytic activity, and uses ther

Details Genes which influence Pichia proteolytic activity, and uses ther Genes which influence Pichia proteolytic activity, and uses ther

1993-07-06

1994-06-28

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

435938, 435 691, C12N 116

Patent

active

053246608

ABSTRACT:
The isolation and characterization of genes involved in proteolytic processing in species of the genus Pichia is described. The availability of such genes has enabled the generation of strains of Pichia which are deficient in proteolytic activity, which strains are useful as hosts for the expression of proteolytically sensitive recombinant products. The isolation and characterization of additional genes from species of the genus Pichia is also described, as well as uses therefore.

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