Genes which influence pichia proteolytic activity, and uses ther

Details Genes which influence pichia proteolytic activity, and uses ther Genes which influence pichia proteolytic activity, and uses ther

1997-01-22

2000-04-18

Achutamurthy, Ponnathapu

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

4352555, 435440, 435938, 536 232, 935 28, 935 69, C12N 114, C12N 1500, C12N 100, C07H 2104

Patent

active

060514191

ABSTRACT:
The isolation and characterization of genes involved in proteolytic processing in species of the genus Pichia is described. The availability of such genes has enabled the generation of strains of Pichia which are deficient in proteolytic activity, which strains are useful as hosts for the expression of proteolytically sensitive recombinant products. The isolation and characterization of additional genes from species of the genus Pichia is also described, as well as uses therefore.

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