Genes which influence pichia proteolytic activity, and uses ther

Details Genes which influence pichia proteolytic activity, and uses ther Genes which influence pichia proteolytic activity, and uses ther

1995-05-16

1997-11-25

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 694, 435232, 43525423, C12P 2106, C12N 988, C12N 119

Patent

active

056911661

ABSTRACT:
The isolation and characterization of genes involved in proteolytic processing in species of the genus Pichia is described. The availability of such genes has enabled the generation of strains of Pichia which are deficient in proteolytic activity, which strains are useful as hosts for the expression of proteolytically sensitive recombinant products. The isolation and characterization of additional genes from species of the genus Pichia is also described, as well as uses therefore.

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