Genes involved in polyketide synthase pathways and uses thereof

Details Genes involved in polyketide synthase pathways and uses thereof Genes involved in polyketide synthase pathways and uses thereof

2008-05-06

2008-05-06

Nashed, Nashaat T. (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S041000, C435S069100, C435S252300, C435S320100

Reexamination Certificate

active

11711809

ABSTRACT:
The subject invention relates to isolated nucleic acid sequences or genes involved in polyketide synthase (PKS) biosynthetic pathways. In particular, such pathways are involved in the production of polyunsaturated fatty acids (PUFAs) such as, for example, Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA). Specifically, the invention relates to isolating nucleic acid sequences encoding proteins involved in eukaryotic PUFA-PKS systems and to uses of these genes and encoded proteins in PUFA-PKS systems, in heterologous hosts, for the production of PUFAs such as EPA and DHA.

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