Genes from the 20Q13 amplicon and their uses

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 2431, C12N 1511

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active

058920102

ABSTRACT:
The present invention relates to cDNA sequences from a region of amplification on chromosome 20 associated with disease. The sequences can be used in hybridization methods for the identification of chromosomal abnormalities associated with various diseases. The sequences can also be used for treatment of diseases.

REFERENCES:
patent: 5472842 (1995-12-01), Stokke et al.
patent: 5633365 (1997-05-01), Stokke et al.
Matthews et al., Anal. Biochem., v. 169, Feb. 1988, 1-25.
Cremer et al., Hum. Genet., v. 80, 1988, 235-246.
Lichter et al., Hum. Genet., v. 80 1988, 224-234.
Kallioniemi et al., Proc. Natl. Acad. Sci., v. 91, 1994, pp. 2156-2160.
Kallioniemi et al., Science, v. 258, Oct. 30, 1992, 818-821.
Wiegant et al., Nucleic Acids. Res, v. 19, 1991, 3237-3241.
J.N. Lucas et al. "Translocations between two specific human chromosomes detected by three-color 'chromosome painting;" Cytogenet Cell Genet vol. 62 pp. 11-12 (1993).
Annika Lindblom et al. "Deletions on Chromosome 16 in Primary Familial Breast Carcinomas Are Associated with Development of Distant Metatases" Cancer Research vol. 53, pp. 3707-3711, Aug. 15, 1993.
Ulf S.R. . Bergerheim et al. "Deletion Mapping of Chromosomes 8, 10, and 16 in Human Prostatic Carcinoma" Genes. Chromosomes& Cancer vol. 3, pp. 215-220 (1991).
Elizabeth Blennow et al. "Complete characterization of a large marker chromosome by reverse and forward chromosome painting" m Genet (1992) vol. 90, pp. 371-374. Received: Jun. 15, 1992/Revised: Jul. 6, 1992.
Stefan Joos et al. "Detection of amplified DNA sequences by reverse chromosomes painting using genomic tumor DNA as probe" m Genet (1993) vol. 90, pp. 584-589. Received: Oct. 30 1993.
Anne Kallioniemi et al. "Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors" Science vol. 258, Oct. 30, 1992 pp. 818-821.
Peter Lichter et al. "High-Resolution Mapping of Human Chromosome 11 by in Situ Hybridization with Cosmid Clones" Science vol. 247 Jan. 5, 1990 pp. 64-69.
Anne Kallioniemi e tal. "ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization" Proc. Acad. Nat. Sci. 89:5321-5325 (1992).
Pinkel et al. "Fluorescence in situ hybridization with human chromosome-specific libraries: Detection of trisomy 21 and translocations of chromosome 4" Proc. Acad. Nat. Sci. 85:9138-9142 (1988).
Stokke et al. "Genetic characterization of 20q amplication in human breast cancer" Abstract submitted to the 43rd Annual Meeting of the American Society of Human Genetics (Appendix 2).
ATCC/NIH Repository Catalogue, 1992, pp. 113-114.
Strokke et al. Genomics 26:134 (1995).
Tanner et al. Increased Copy Number on 20q13 in Breast Cancer: Defining the Critical Region and Exclusion of Candidates Genes. Cancer Research. Aug. 15, 1994, vol. 54, pp. 4257-4260.
Gyapay et al. The 1993-1994 genethon human genetic linkage map. Nature Genetics. Jun. 1994, vol. 7, pp. 246-339.
Datebase EST-STS on MPsrch Accession No. G08049, Murray et al. 'Cooperative human linkage center Aug. 08, 1995.
Hillier et al. 1995. Accession No. H95828, H94297, WO5407, H12950, H16954, H40682, H78571/GenBank.
Robinson, NJ et al. 1994. Accession No. Z47159 GenBank.
Schable, K. et al. 1993. Accession No. X76070 Genebank.
Ferrari, DM et al., 1996, Accession No. X94910 Genebank.
Short, JM et al. 1988. Nucleic Acid Res. 16(15): 7583-7600.
Okeebo, K. et al. 1994. DNA Res. 1:37-45.
Pawla K, A. et al. 1995. Genomics 26:151-158.

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