Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal
Patent
1994-06-08
1997-06-17
Fox, David T.
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
Transgenic nonhuman animal
435 691, 435 711, 435117, 4351723, 43525233, 43525234, 4353201, 536 232, 536 237, A01H 500, C12N 1531, C12N 1582, C12P 1700, C12R 138
Patent
active
056399499
ABSTRACT:
The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.
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Hammer Philip E.
Hill Dwight Steven
Lam Stephen Ting
Ligon James M.
Ryals John Andrew
Ciba-Geigy Corporation
Fox David T.
Meigs J. Timothy
Walsh Andrea C.
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