Genes for the synthesis of antipathogenic substances

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...

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435 41, 4352533, C12N 900, C12N 120, C12P 100

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056795602

ABSTRACT:
The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.

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