Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-02-27
2007-02-27
Navarro, Mark (Department: 1645)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S069100
Reexamination Certificate
active
11073560
ABSTRACT:
A plurality of primer sets are designed based on a region where conservation at the amino acid level is observed among various microorganisms for known gene sequences corresponding to a gene coding for an enzyme of the L-amino acid biosynthetic pathway derived fromCorynebacterium thermoaminogenes, preferably an enzyme that functions at a higher temperature compared with that ofCorynebacterium glutamicum. PCR is performed by using the primers and chromosomal DNA ofCorynebacterium thermoaminogenesas a template. The primers with which an amplification fragment has been obtained are used as primers for screening to select a clone containing a target DNA fragment from a plasmid library of chromosomal DNA ofCorynebacterium thermoaminogenes.
REFERENCES:
patent: 5250423 (1993-10-01), Murakami et al.
patent: 5250434 (1993-10-01), Yamada et al.
patent: 6696561 (2004-02-01), Pompejus et al.
patent: 616168 (1988-02-01), None
patent: 61-268185 (1986-11-01), None
patent: 63-119688 (1988-05-01), None
patent: 63-214189 (1988-09-01), None
patent: 2-291276 (1990-04-01), None
patent: 4-4887 (1992-01-01), None
patent: 5-56782 (1993-03-01), None
patent: 5-244958 (1993-09-01), None
patent: 6-504548 (1994-03-01), None
patent: 7-63383 (1995-07-01), None
patent: 7-121227 (1995-12-01), None
patent: 8-66189 (1996-03-01), None
patent: 8-196280 (1996-08-01), None
patent: 10-165180 (1998-06-01), None
patent: 10-234371 (1998-09-01), None
patent: 11-196887 (1999-07-01), None
patent: 92/18635 (1992-10-01), None
patent: 94/08016 (1994-04-01), None
patent: 95/23224 (1995-08-01), None
patent: 95/34672 (1995-12-01), None
patent: 96/32484 (1996-10-01), None
patent: 97/48790 (1997-12-01), None
patent: 99/18228 (1999-04-01), None
K. Takai, et al., “PPC, The Gene for Phosphoenolpyruvate Carboxylase From an Extremely Thermophilic Bacterium, Rhodothermus Obamensis: Cloning, Sequencing and Overexpression inEscherichia coli”, Microbiology, vol. 144, No. 5, pp. 1423-1434, 1989.
D. Wereecke, et al., “Cloning and Sequence Analysis of the Gene Encoding Isocitrate Lyase From Rhodococcus Fascians”, Gene, vol. 145, No. 1, pp. 109-114, 1994.
W. Jager, et al., “A Corynebacterium Glutamicum Gene Encoding a Two-Domain Protein Similar to Biotin Carboxylases and Biotin-Carboxyl-Carrier Proteins”, Arch. Microbiol., vol. 166, No. 2, pp. 977-984, 1996.
S. Donadio. et al., “Erythromycin Production in Saccharopolyspora Erythraea Does Not Require a Functional Propionyl-COA Carboxylase”, Mol. Microbiol., vol. 19, pp. 977-984, 1996.
E. Kumura, et al., “Molecular Cloning of a Novel Gene, DTSR, Which Rescues the Detergent Sensitivity of a Mutant Derived From Brevibacterium Lactofermentum”, Biosci. Biotechnol. Biochem., vol. 60, pp. 1565-1570, 1996.
A.M. Alves, et al., “Characterization and Phylogeny of the PFP Gene of Amycolatopsis Methanolica Encoding PPI-Dependent Phosphofructokinase”, J. Bacteriol., vol. 178, pp. 149-155, 1996.
A.M.C.R. Alves, et al., “Identification of ATP-Dependent Phosphofructokinase as a Regulatory Step in the Glycolytic Pathway of the Acnomycete Streptomyces Coelicolor”, Appl. Environ. Microbiol., vol. 63, pp. 951-956, 1997.
W. Kronemeyer, et al., “Structure of the Gluabcd Cluster Encoding the Glutamate Uptake System of Corynebacterium Glutamicum”, J. Bacteriol., vol. 177, pp. 1152-1158, 1995.
C. Rollin, et al, “13C-NMR Studies of Corynebacterium Melassecola Metabolic Pathways”, Eur. J. Biochem., vol. 227, No. 1-2, pp. 488-493, 1995.
S.Hein, et al., “Biochemical and Molecular Characterization of the Alcaligenes Eutrophus Pyruvate Dehydrogenase Complex and Identification of New Type of Dihydrolipoamide Dehydrogenase”, J. Bacteriol., vol. 176, pp. 4394-4408, 1994.
P.E. Stephens, et al., “The Pyruvate Dehydrogenase Complex ofEscherichia coliK12. Nucleotide Sequence Encoding the Pyruvate Dehydrogenase Component”, Euro. J. Biochem., vol. 133, pp. 155-162, 1983.
M.P. Ruklish, et al., “The Functioning of the Tricarboxylic Acid Cycle in Brevibacterium Flavum and Micrococcus Glutamicus”, Mikrobiologia, vol. 56, No. 5, pp. 759-763, 1987.
J.M. Mengaud, et al., “The Major Iron-Containing Protein of Legionella Pneumophila is an Aconitase Homologous With the Human Iron-Responsive Element-Binding Protein”, J. Bacteriol., vol. 175, pp. 5666-5676, 1993.
C. Prodromou, et al., “The Aconitase ofEscherichia coli.Nucleotide Sequence of the Aconitase Gene and Amino Sequence Similarity With Mitochondrial Isopropylmalate Isomerases”, Eur. J. Biochem., vol. 204, pp. 599-609, 1992.
B.J. Eikmanns, et al., “Cloning, Sequence Analysis, Expression, and Inactivation of the Corynebacterium Glutamicum ICD Gene Encoding Isocitrate Dehydrogenase and Biochemical Characterization of the Enzyme”, J. Bacteriol., vol. 177, pp. 774-782, 1993.
A. Ishi, et al., “Genes Encoding Two Isocitrate Dehydrogenase Isozymes of a Psychrophilic Bacterium, Vinrio sp. Strain Abe-1”, J. Bacteriol., vol. 175, pp. 6873-6880, 1993.
B.J. Eikmanns, et al., “Corynebacterium Glutamicum LPD Gene, Complete CDS”, Genbank Acc. No. Y16642, Feb. 1, 1999.
E.R. Boermann, et al., “Molecular Analysis of the Corynebacterium Glutamicum GDH Gene Encoding Glutmade Dehydrogenase”, Mol. Microbiol., vol. 6, pp. 317-326, 1992.
B.J. Eikmanns, et al., “Nucleotide Sequence, Expression and Transcriptional Analysis of the Corynebacterium Glutamicum GLTA Gene Encoding Citrate Syntase”, Microbiology, vol. 140, pp. 1817-1828, 1994.
M.A. Pardo, et al., “Nodulationg Ability of Rhizobium Tropici is Conditioned by Plasmid-Encoded Citrate Syntase”, Mol. Microbil., vol. 11, pp. 315-321, 1994.
D.J. Reinscheid, et al., “Characterization of the Isocitrate Lyase Gene From Corynebacterium Glutamicum and Biochemical Analysis of the Enzyme”, Journal of Bacteriology, vol. 176, No. 12, XP-009014047, pp. 3474-3483, Jun. 1994.
R.M. Chell, et al., “Isolation and Characterization of Isocitrate Lyase From a Thermophilic Bacillus sp”, Biochemical Journal, vol. 173, No. 1, XP-001156125, pp. 165-177, 1978.
J.M. Muir, et al., “Citrate Synthase From the Hyperthermophilic Archaeon, Pyrocococcus Furiosus”, Protein Engineering, vol. 8, No. 6, XP-009020603, pp. 583-892, 1995.
K.L. Britton, et al., “Insights into Thermal Stability From a Comparison of the Glutamate Dehydrogenases From Pyrococcus Furiosus and the Thermococcus Litoralis”, European Journal of Biochemistry, vol. 229, No. 3, XP-009027920, pp. 688-695, 1995.
J.H.G. Lebbink, et al., “Glutamate Dehydrogenase From Hyperthermophilic Bacteria and Archaea: Determinants of Thermostability and Catalysis at Extremely High Temperatures”, Journal of Molecular Catalysis B: Enzymatic, vol. 7, No. 1-4, XP-001180258, pp. 133-145, Sep. 15, 1999.
Rudinger (Peptide Hormones, University Park Press, Jun. 1976, pp. 1-7).
Y. Usuda, et al., “Molecular Cloning of the Corynebacterium Glutamicum (‘Brevibacterium Lactofermentum’ AJ12036) ODHA Gene Encoding a Novel Type of 2-Oxoglutarate Dehydrogenase”, Microbiology, 1996, 142, pp. 3347-3354.
Kawarabayasi, Y., et al., “ Complete Genome Sequence of an Aerobic Hyper-thermophilic Crenarchaeon, Aeropyrum pernix K1,” DNA Research 6, pp. 83-101, 1999, XP-002395273.
Sutherland, K. J., et al., “Citrate Synthase from the Thermophilic Archaebacterium Thermoplasma acidophilium Cloning and Sequencing of the Gene,” European Journal of Biochemistry, vol. 194, No. 3, 1990, pp. 839-844, XP002395031.
Akiyoshi Naoki
Hirano Seiko
Kawahara Yoshio
Kimura Eiichiro
Kurahashi Osamu
Ajinomoto Co. Inc.
Navarro Mark
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