Genes for heat resistant enzymes of amino acid biosynthetic...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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C435S069100

Reexamination Certificate

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07125977

ABSTRACT:
A plurality of primer sets are designed based on a region where conservation at the amino acid level is observed among various microorganisms for known gene sequences corresponding to a gene coding for an enzyme of the L-amino acid biosynthetic pathway derived fromCorynebacterium thermoaminogenes,preferably an enzyme that functions at a higher temperature compared with that ofCorynebacterium glutamicum.PCR is performed by using the primers and chromosomal DNA ofCorynebacterium thermoaminogenesas a template. The primers with which an amplification fragment has been obtained are used as primers for screening to select a clone containing a target DNA fragment from a plasmid library of chromosomal DNA ofCorynebacterium thermoaminogenes.

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