Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1992-03-20
1994-09-20
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
4241851, 424581, 424582, 424811, 4351721, 4351723, 530350, 530853, 536 235, 536 231, A61K 3700, A61K 3900, C12N 1512
Patent
active
053488660
ABSTRACT:
This invention relates to a DNA sequence comprising at least part of a porcine zona pellucida PZP-4.alpha. or -4.beta. gene coding for an amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 2, respectively, in SEQUENCE LISTING.
This invention also relates to an expression system and to expression of said DNA.
In addition, this invention relates to an immunogenic recombinant polypeptide or peptide which comprises at least part of said amino acid sequence and which is obtained by expressing said DNA, and to a contraceptive vaccine for use in human or other animals which comprises said polypeptide or peptide as an active ingredient.
REFERENCES:
patent: 4996297 (1991-02-01), Dunbar
Liang, Li-Fang. 1990. Oocyte-specific expression of mouse-ZP-2: developmental regulation of the Zona Pellucida genes. Mol. & Cell. Biolog. 10(4): 1507-1515.
Young, R. A. et al. Proc. Natl. Acad. Sci. 80: 1194-1198 (1983).
Sambrook, J et al. Molecular Cloning Cold Spring Harbor Labs (1989) pp. 11.2-11.19.
Jurrien, D. 1990 Contraceptive Vaccine Based on Cloned Zona Pellucida Genes. NTIS order #Pat-Appl-7-364-379.
Moller, Christopher C. et al. 1989 Characterization of a Proteinase That Cleaves Zona Pellucida Glycoprotein ZP2 Following Activation of Mouse Eggs. Dev. Biol. 132:103-112.
Serrano, H. et al Dec. 8-12, 1991 cDNA Library Expressing Ovarian Pig Genes. J. Cell Biology. 115 (3 part 2) 462A.
Bleil, Jeffrey D. 1988. Identification of a Z.sup.0 Sperm Receptor in the Mouse Egg Zona Pellucida: Role in Maintenance of Binding of Acrosome-Reacted Sperm to Eggs. Dev. Biol. 128:376-385.
M Koyama, et al., Biology of Reproduction, 45:727-735 (1991).
Database WPIL, Week 8831, Derwent Publications, AN 88-215529 (31) of JP-A-63 150 299 (TOA Nenryo Kogyo KK) Jun. 22, 1988 Abstract.
Database WPIL. Week 9033, Derwent Publications, AN90-250685 (33) of JP-A-2 174 677 (Tonen Corp) Jul. 6, 1990 Abstract.
Koyama, et al., Journal of Reproductive Immunology, 19:131-148 (1991).
Biological Abstracts, A. Hasegawa, Abstract No. 91113039 of Acta Obstetrica et Gynaecologica Japonica, 43(2):221-226 (1991).
P. M. Wassarman, "Zona Pellucida Glycoproteins", Ann. Rev. Biochem, 1988, 57, pp. 415-442.
A. G. Sacco, "Zona Pellucida", Am. J. Reproductive Immunology & Microbiology 1987, 15, pp. 122-130.
Akatani Akiko
Isojima Shinzo
Okazaki Yuichi
Sugimoto Masanobu
Conlin David G.
Isojima Shinzo
Nucker Christine M.
Resnick David S.
Tonen Corporation
LandOfFree
Genes encoding porcine zona pellucida protein PZP-4, expression does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Genes encoding porcine zona pellucida protein PZP-4, expression , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Genes encoding porcine zona pellucida protein PZP-4, expression will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2429796