Genes encoding platelet aggregation inhibitors

Details Genes encoding platelet aggregation inhibitors Genes encoding platelet aggregation inhibitors

1993-05-24

1996-03-05

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 43525231, 43525233, 4352542, 536 235, C12N 121, C12N 1571, C12N 119, C12N 1512

Patent

active

054967244

ABSTRACT:
An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolated and purified PAI from several of these active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K*-(G/Sar)-D wherein K* is a modified lysyl residue of the formula

REFERENCES:
patent: 4652639 (1987-03-01), Stabinsky et al.
Knudson et al Exp. Cell Res (1988) pp. 42-49 (1988).
Huang et al Toxicon 22(2) 243-252 (1984).
Huang et al BBACA 925(3) 248-257 (1987).
Kosogi et al Snake 17(2) pp. 117-123 (1985).
Ouyang et al Toxican 21(6) pp. 797-804 (1983).

Affiliated with

Also associated with

Rating

Genes encoding platelet aggregation inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Genes encoding platelet aggregation inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Genes encoding platelet aggregation inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1412449