Genes encoding nematode-active toxins cloned from bacillus thuri

Details Genes encoding nematode-active toxins cloned from bacillus thuri Genes encoding nematode-active toxins cloned from bacillus thuri

1990-07-24

1994-01-25

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 43525233, 4352404, 536 2371, 530350, 935 9, 424 93L, C12N 120, C12N 1500, A01N 6300

Patent

active

052815307

ABSTRACT:
Nematicidal .delta.-endotoxin encoding genes have been cloned from a novel Bacillus thuringiensis isolate known as B.t. PS17. These novel genes, designated B.t. PS17a, B.t. PS17b, Bt. PS17d, and B.t. PS17e, can be transferred to various microbial and plant hosts via known techniques. In the microbial or plant host, one or more of the genes of the invention can be used to express the novel nematicidal toxins to control susceptible nematodes.

REFERENCES:
Prichard, R. K., C. A. Hall, J. D. Kelly, I. C. A. Martin, and A. D. Donald (1980) "The Problem of Anthelmintic Resistance in Nematodes," Austr. Vet. J. 56:239-251.
Coles, G. C. (1986) "Anthelmintic Resistance in Sheep," In Veterinary Clinics of North America: Food Animal Practice, vol. 2:423-432 (Herd, R. P., ed.), W. B. Saunders, New York.
Bottjer, K. P., L. W. Bone, and S. S. Gill (1985) "Nematoda: Susceptibility of the Egg to Bacillus thuringiensis Toxins," Experimental Parisitology 60:239-244.
Ignoffo, C. M., and V. H. Dropkin (1977) "Deleterious Effects of the Thermostable Toxin of Bacillus thuringiensis on Species of Soil-Inhabiting, Myceliophagus, and Plant-Parasitic Nematodes," J. Kansas Entomol. Soc. 50:394-398.
Ciordia, H., and W. E. Bizzell (1961) "A Preliminary Report on the Effects of Bacillus thuringiensis var. thuringiensis Berliner on the Development of the Free-Living Stages of Some Cattle Nematodes," J. Parisitol. 47:41 (abstract).
Prefontaine et al., App. Env. Mic., vol. 53, #12, pp. 2808-2814, Dec. 1987.
Haider, et al. Gene, 52, pp. 285-290, 1987.

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