Genes encoding melanocertin-4 receptor and methods of use

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 72, 4353201, 435325, 4352523, 43525411, 435 691, C12N 1510, C12N 510, C12N 112, G01N 3353

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057032203

ABSTRACT:
Genes encoding melanocortin receptors have been identified, isolated, cloned and localized to their chromosomal positions. These genes have been used to transfect mammalian cells lacking endogenous melanocortin receptors to induce expression. Additionally, melanocortin receptor binding, secondary signalling, and tissue distribution has been characterized. The genes and their gene products may therefore be used to provide therapeutic vehicles for the treatment of processes involving the function of melanocortin receptors.

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