Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-04-03
1999-04-06
Elliott, George C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 6951, 4351721, 4353201, 435325, 536 231, 536 235, 536 2352, C07H 2102, C07H 2104, C12N 1500, C12N 1511
Patent
active
058916660
ABSTRACT:
Disclosed are nucleotide sequences encoding a novel polypeptide termed LSIRF. Also disclosed are methods of preparing the polypeptide and uses thereof.
REFERENCES:
Sommer et al, "Minimal Sequence Requirements for PCR Primers" NAR vol. 17(16):6749, 1989.
Driggers et al., An interferon .gamma.-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes, Proc. Natl. Acad. Sci. USA, vol. 87, pp. 3743-3747, May 1990.
Eisenbeis et al., Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator, Genes & Development, vol. 9, pp. 1377-1387, 1955.
Harada et al., Structurally Similar but Functionally Distinct Factors, IRF-1 and IRF-2, Bind to the Same Regulatory Elements of IFN and IFN-Indujcible Genes, Cell, vol. 58, pp. 729-739, Aug. 25, 1989.
Matsuyama et al., Molecular cloning of LSIRF, a lymphoid-specific member of the inferferon regulatory factor family that binds the interferon-stimulated response element (ISRE), Nucleic Acids Research, vol. 23, No. 12, pp. 2127-2136, 1995.
Miyamoto et al., Regulated Expression of a Gene Encoding a Nuclear Factor, IRF-1, That Specifically Binds to IFN-.beta. Gene Regulatory Elements, Cell, vol. 54, pp. 903-913, Sep. 9, 1988.
Veals et al., Subunit of an Alpha-Interferon-Responsive Transcription Factor Is Related to Interferon Regulatory Factor and Myb Families of DNA-Binding Proteins, Molecular and Cellular Biology, vol. 12, No. 8, pp. 3315-3324, Aug. 1992.
Grossman Alex
Matsuyama Toshifumi
Amgen Canada Inc.
Elliott George C.
Levy Ron K.
McGarry Sean
Odre Steven M.
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