Genes encoding carotenoid compounds

Details Genes encoding carotenoid compounds Genes encoding carotenoid compounds

2005-08-16

2005-08-16

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a carotene nucleus

C435S252300, C435S254200, C435S254110, C435S257200, C435S183000, C435S419000, C435S254210, C435S252200, C435S254600, C435S252310, C435S254230, C435S252200, C435S252320, C435S252330, C435S252340, C435S252350, C435S320100, C435S254300, C536S023200

Reexamination Certificate

active

06929928

ABSTRACT:
A unique carotenogenic biosynthetic gene cluster has been isolated fromPanteoa agglomeransstrain DC404, wherein the genetic organization of the cluster is crtE-idi-crtY-crtI-crtB-crtZ. The genes contained within this cluster encode geranylgeranyl pyrophosphate (GGPP) synthetase (CrtE), isopentenyl pyrophosphate isomerase (Idi), lycopene cyclase (CrtY), phytoene desaturase (CrtI), phytoene synthase (CrtB), and β-carotene hydroxylase (CrtZ). The gene cluster, genes and their products are useful for the conversion of farnesyl pyrophosphate to carotenoids. Vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes by recombinant DNA technology in transformed host organisms are disclosed.

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