Genes encoding branched-chain alpha-ketoacid dehydrogenase compl

Details Genes encoding branched-chain alpha-ketoacid dehydrogenase compl Genes encoding branched-chain alpha-ketoacid dehydrogenase compl

1995-06-07

1998-03-17

Ketter, James

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

C12N 904

Patent

active

057285616

ABSTRACT:
The present invention relates to novel DNA sequences that encode for the branched-chain alpha-ketoacid dehydrogenase complex of an organism belonging to the genus Streptomyces and to novel polypeptides produced by the expression of such sequences. It also relates to novel methods of enhancing the production of natural avermectin and of producing novel avermectin through fermentation.

REFERENCES:
Wexler et al. 1991 Febs Lett. 282(1) 209-213.
Ovnic et al. 1991 Genomics 11 pp. 956-967.

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