Genes encoding and method of expressing an enzyme: phthalyl amid

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435227, 435228, 4353201, 43525233, 43525235, 536 232, 536 241, C12N 978, C12N 121, C12N 1555

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active

054515220

ABSTRACT:
Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides DNA compounds encoding the phthalyl amidase enzyme and methods for expressing such compounds. The present invention also provides recombinant DNA vectors encoding phthalyl amidase and host cells transformed with these DNA vectors.

REFERENCES:
patent: 4977089 (1990-12-01), Kovacevic et al.
patent: 5032510 (1991-07-01), Kovacevic et al.
Smith, Gale E., et al., Molecular and Cellular Biology, vol. 3, No. 12, pp. 2156-2165, Dec. 1983.
Yang et al., J. Biol. Chem., 268:10870, 1993.

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