Genes encoding and method of expressing a novel enzyme: phthalyl

Details Genes encoding and method of expressing a novel enzyme: phthalyl Genes encoding and method of expressing a novel enzyme: phthalyl

1995-05-22

1996-08-06

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

930300, 536 241, 935 6, 435228, C12N 980, C12N 1574

Patent

active

055434975

ABSTRACT:
Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides DNA compounds encoding the phthalyl amidase enzyme and methods for expressing such compounds. The present invention also provides recombinant DNA vectors encoding phthalyl amidase and host cells transformed with these DNA vectors.

REFERENCES:
patent: 4977089 (1990-12-01), Kovacevic et al.
patent: 5032510 (1991-07-01), Kovacevic et al.
Smith, Gale E., et al., Molecular and Cellular Biology, vol. 3, No. 12, pp. 2156-2165, Dec. 1983.
Yang et al., Journal of Biological Chemistry, vol. 268, No. 15, pp. 10870-10875, 1993.

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