Genes differentially expressed in metastatic and non-metastatic

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

536 2431, C07H 2102, C07H 2104

Patent

active

055390960

ABSTRACT:
The present invention relates to polynucleotide sequences and proteins that are differentially expressed in invasive or metastasis cancer cells during malignant tumor progression of cancer, for example in rhabdomyosarcoma and which may thus serve as general molecular markers in metastatic disease as well as providing a basis for therapy. The present invention also relates to a method of diagnosis of malignant diseases based on the detection of such markers.

REFERENCES:
Babal F., J. Ultrastructure Res., 1976, 56:287-303.
Frixen U. H. et al., Journal of Cell Biology, 1991, 113(1):173-85.
Phillips SM et al., Journal of the National Cancer Institute, 1990, 82(3):199-203.
Ebralidze A et al., Genes & Development, 1989, 3(7):1086-93.
Murakami A et al., Cell Growth & Differentiation, 1990, 1(5):225-31.
Gunthert U et al., Cell, 1991, 65:13.
Schalken JA et al., Cancer Res., 1988, 48:2042-2046.
Wallet V et al., Journal of the National Cancer Institute, 1990, 82(14):1199-202.
Dear TN et al., Cancer Research, 1990, 50(5):1667.
Elvin P et al., Br. J. Cancer, 1988, 57:36-42.
Liotta LA, Amer. J. Pathol., 1984, 117:339-348.
Sharp MGF et al., Br. J. Cancer, 1990, 61:83-88.
Basset P et al., Nature, 1990, 348:699-704.
Adams SM et al., Human molecular genetics, 1992, 1(2):91-96.
Adams SM et al., Br. J. Cancer, 1992, 65:65-71.
Armstrong PB, Invasiveness of non-malignant cells. In: Invastion. Experimental and clinical implications. Mareal MM and Calman, KC, ed. Oxford University Press. Oxford, 1984.
Babai F, and Royal A, Rat myoblastic sarcoma cell lines: A model for the study of invasion, metastatis and myogenic differentiation. Lab. Investigation, 1994, 70:907-915.
Sambrook J, Fritsch EF, and Maniatis T. Molecular cloning: A laboratory manual, second edition, Cold Spring Harbor Laboratory Press, 1989.
Croze F et al., Endocrinology, 1990, 127:2665-2672.
Mauxion F et al., Nucleic Acids Res., 1987, 15:7638.
Matrisian LM et al., Nucleic Acids Res, 1985, 13:711-726.
Grenett HE et al., Gene, 1992, 110:239-243.
Kuwano Y et al., Biochem. Biophys. Res. Commun., 1991, 175:551-555.
Devi KR et al., Biochem. Biophys. Acta, 1989, 1008:258-262.
Wool IG et al., Biochimie, 1991, 73:861-870.
Michaelson J, Immunogenetics, 1983, 17:219.
Ljunggren H-G et al., J. Immunol., 1990, 145:380-386.
Argiles JM et al., Medical Hypotheses, 1990, 32(2):151-155.
Hart IR et al., Biochimica Et Biophysica Acta, 1989, 989(1):65-84.
Steeg PS et al., J. Natl. Cancer Inst., 1988, 80:200-204.
Dear TN et al., Cancer Res., 1989, 49:5323-5328.
Kondoh et al., Cancer Res., 1992, 52:791-796.
Pogue-Geile et al., Mol. and Cell. Biol., 1991, 11:3842-3849.
Rabbitts, T. H. et al., Nature Genetics, 1993, 4:175-180.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Genes differentially expressed in metastatic and non-metastatic does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Genes differentially expressed in metastatic and non-metastatic , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Genes differentially expressed in metastatic and non-metastatic will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-714098

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.