Genes conferring on yeasts a resistance to herbicides

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi

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435255, 4351721, 4351723, 4353171, 935 28, 935 69, C12N 1500, C12N 500, C12N 700

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047450657

ABSTRACT:
Disclosed is an autoreplicative plasmid containing DNA which encodes herbicide resistance, such that the plasmid is capable of transforming a yeast cell to become resistant to one or more organic herbicide growth inhibitors. Also disclosed is a process for the selective culture of yeasts transformed by the plasmid.

REFERENCES:
patent: 4443971 (1984-04-01), Chaleff
Dumas et al. 1984 "Molecular Cloning and DNA Sequence of the Yeast ILV2 Gene" (Abstract) Am Soc. Microbiol Abstracts of Ann Meeting.
Hinnen et al. 1978 "Transformation of Yeast" Proc. Natl. Acad. Sci. vol. 75, pp. 1929-1933.
Jimenez et al. 1980 "Expression of a Transposable Antibiotic Resistance Element in Saccharomyces" Nature vol. 287, 869-871.
Falco et al. 1985"Genetic Analysis of Mutants of Saccharomyces ceruisiae resitant to the Herbicide Sulfometuron Methyl" Genetics vol. 109, 21-35.
Stalker et al. 1985 "A Single Amino Acid Substitution in the enzyme 5-Enolpyrulvylshikimate-3-Phosphate Synthase . . . J. Biol. Chem. vol. 260(8) 4724-4728.
Hirschberg et al. 1983 "Molecular Basis of Herbicide Resistance in Amaranthus hybridus", Science vol. 222 1346-1348.
Hughes 1983 "Selection for Herbicide Resistance" in Handbook of Plant Cell Culture vol. 1 Evans et al. (Eds) pp. 422-460.
Rogers, S. G., "Genetically Engineered Glyophosphate Tolerance in E. Coli", J. Cell Biochem Suppl. 713: 1213, p. 268, 1983.

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