Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-06-26
2007-06-26
Brusca, John S. (Department: 1631)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S069100, C435S320100, C435S325000, C435S440000, C530S350000, C530S387100
Reexamination Certificate
active
10329079
ABSTRACT:
Genes and proteins involved in the biosynthesis of lipopeptides by microorganisms, in particular the nucleic acids forming the biosynthetic locus for the A54145 lipopeptide fromStreptomyces fradiaeand the A54145-like lipopeptide fromStreptomyces refuineus. These nucleic acids can be used to make expression constructs and transformed host cells for the production of lipopeptides. The genes and proteins allow direct manipulation of lipopeptides and related chemical structures via chemical engineering of the proteins involved in the biosynthesis of A54145.
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Farnet Chris M.
Staffa Alfredo
Zazopoulos Emmanuel
Brusca John S.
Cubist Pharmaceuticals, Inc.
Negin Russell S.
Sughrue & Mion, PLLC
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