Genes and proteins for treating cystic fibrosis

Details Genes and proteins for treating cystic fibrosis Genes and proteins for treating cystic fibrosis

1994-03-23

1997-06-17

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 536 235, 536 243, C12N 121, C12N 1563, C07H 2104

Patent

active

056396619

ABSTRACT:
Disclosed are genes encoding novel CF monomer proteins which have cystic fibrosis transmembrane conductance regulator (CFTR) protein function.

REFERENCES:
patent: 5240846 (1993-08-01), Collins et al.
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Kartner, et al., "Mislocalization of .DELTA.F508 CFTR in Cystic Fibrosis Sweat Gland", Nature Genetics, vol. 1, pp. 321-327, Aug. 1992.
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Gregory, et al., "Expression and Characterization of the Cystic Fibrosis Transmembrane Conductance Regulator", Nature, vol. 347, pp. 382-386, Sep. 27, 1990.
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Flotte, et al., "Expression of the Cystic Fibrosis Transmembrane Conductance Regulator from a Novel Adeno-Associated Virus Promoter", The Journal of Biological Chemistry, vol. 268, No. 5, pp. 3781-3790, Feb. 15, 1993.
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