Genes and proteins, and their use

Details Genes and proteins, and their use Genes and proteins, and their use

2005-05-10

2005-05-10

Smith, L. F. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S190100, C435S069300, C435S183000, C435S252300, C435S320100, C530S350000, C536S023700

Reexamination Certificate

active

06890539

ABSTRACT:
A protein from Group BStreptococcusis shown to be an outer surface protein and is a useful target for antimicrobial therapy.

REFERENCES:
patent: 0006736 (1999-07-01), None
Parsons, J.A., University Park Press, Jun. 1976, p. 6.*
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Jobling et al. Mol. Microbiol. 1991, 5(7): 1755-67.*
Coffey, T. et al. (Jun. 1998) “Recombinational exchanges at the capsular polysacchairde biosynthesis locus . . . ”Molecular Microbiology27:73-83; EMBL Database Accession No. 054547 Sequence ID 054547. Sequence only.
Giffard, Philip M., Catherine Rathsam, Edward Kwan et al. (1993) “The ftf gene encoding the cell-bound fructosyltransferase ofStreptococcus salivariusATCC 25975 is preceded by an insertion sequence and followed by FUR1 and clpP homologues”Journal of General Microbiology139:913-920.
Giffard, Philip M. et al. Sequence ID CLPP_STRSL, Jun. 1, 1994, EMBL Database Accession No P36398.
Larsson, Charlotte, Margaretha Stålhammar-Carlemalm, Gunnar Lindahl (Sep. 1996) “Experimental Vaccination Against Group B Streptococcus, an Encapsulated Bacterium, with Highly Purified Preparations of Cell Surface Proteins Rib and α”Infection and Immunity64(9):3518-3523.
Maurizi, Michael R., William P. Clark, Yoko Katayama et al. (Jul. 1990) “Sequence and Structure of Clp P, the Proteolytic Component of the ATP-dependent Clp Protease ofEscherichia coli” The Journal of Biological Chemistry265(21):12536-12545.
Tsukioka, Yuichi, Yoshihisa Yamashita, Takahiko Oho et al. (Feb. 1997) “Biological Function of the dTDP-Rhamnose Synthesis Pathway inStreptococcus mutans” Journal of Bacteriology179(4):1126-1134.
Wastfelt, Maria, Margaretha Stalhammar-Carlemalm, Anne-Marie Delisse et al. (Aug. 1996) “Identification of a Family ofStreptococcalSurface Proteins with Extremely Repetitive Structure”The Journal of Biological Chemistry271(31):18892-18897.
Yuichi, Tsukioka et al., Sequence ID P95779, May 1, 1997, EMBL Database Accession No P95779.
Ellis, R.W. “New Technologies for Making Vaccines” in Vaccines, Plotkin, S.A. and Mortimer, E.A., Eds., Chapter 29, pp. 568-575, published by W.B. Saunders Company (Philadelphia), 1988.

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