Genes and polypeptides relating to human pancreatic cancers

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

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C530S333000

Reexamination Certificate

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07943730

ABSTRACT:
The present application provides novel human genes C1958V1 or C1958V2 whose expression is markedly elevated in pancreatic cancers compared to corresponding non-cancerous tissues. The genes and polypeptides encoded by the genes can be used, for example, in the diagnosis of pancreatic cancer, and as target molecules for developing drugs against the disease.

REFERENCES:
patent: 6429302 (2002-08-01), Kennedy
patent: 2005/0260639 (2005-11-01), Nakamura et al.
patent: 2006/0024692 (2006-02-01), Nakamura et al.
patent: WO 98/53319 (1998-11-01), None
patent: WO 98/53319 (1998-11-01), None
patent: WO 99/31274 (1999-06-01), None
patent: WO 99/31274 (1999-06-01), None
patent: WO 99/67386 (1999-12-01), None
patent: WO 99/67386 (1999-12-01), None
patent: WO 00/55350 (2000-09-01), None
patent: WO 01/09318 (2001-02-01), None
patent: WO 01/40466 (2001-06-01), None
patent: WO 01/55314 (2001-08-01), None
patent: WO 01/55314 (2001-08-01), None
patent: WO 01/55314 (2001-08-01), None
patent: WO 01/94629 (2001-12-01), None
patent: WO 01/94629 (2001-12-01), None
patent: WO 02/29103 (2002-04-01), None
patent: WO 02/29103 (2002-04-01), None
patent: WO 02/068579 (2002-09-01), None
patent: WO 02/068579 (2002-09-01), None
patent: WO 03/054152 (2003-07-01), None
patent: WO 2004/031410 (2004-04-01), None
patent: WO 2004/031410 (2004-04-01), None
Zips et al. (2005, In Vivo, 19:1-7).
Stein et al (Cancer Research, Apr. 2004, 64:2805-2816).
Drexler et al (Leukemia and Lymphoma, 1993, 9:1-25).
Zellner et al (Clin. Can. Res., 1998, 4:1797-17802).
Slamon et al, (Cancer Cells, 1989, 7:371-384).
Ausubel, et al.,Current Protocols in Molecular Biology, Section 9, pp. 9-1-9-14, 3rdEdition, Wiley & Sons, NY (1995).
Crnogorac-Jurcevic, Tatjana et al.; “Gene expression profiles of pancreatic cancer and stromal desmoplasia”;Oncogene20:7437-7446 (2001).
Crnogorac-Jurcevic, Tatjana et al; “Expression profiling of microdissected pancreatic adenocarcinomas”;Oncogene21:4587-4594 (2002).
Drexler, et al.,Leukemia and Lymphoma, vol. 9, pp. 1-25 (1993).
Gress, T.M. et al.; “A pancreatic cancer-specific expression profile”,Oncogene13:1819-1830 (1996).
Han, Haiyong et al.; “Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray”;Cancer Research62:2890-2896 (May 15, 2002).
Iacobuzio-Donahue, Christine A. et al.; “Discovery of novel tumor markers of pancreatic cancer using global gene expression technology”;Am. J. Pathol. 160:1239-1249 (2002).
Jordan, Mary Ann and Leslie Wilson; “Microtubules and actin filaments: dynamic targets for cancer chemotherapy”;Current Opinion in Cell Biology10:123-130 (1998).
Nakamura, Toru et al.; “Genome-wide cDNA microarray analysis of gene-expression profiles of pancreatic cancer using cancer cells and normal ductal epithelial cells purely selected by laser microdissection”;Proceedings of the American Associate for Cancer Research44(2nd ed):1205, Abstract #6036 (Jul. 2003).
Nakamura, Toru et al,; “Isolation and characterization of a novel gene as diagnostic and therapeutic target for pancreatic cancer”;Cancer Science94(Suppl):483-484, Abstract #3420-PA (2003) [Proceedings of the 62nd Annual Meeting of the Japanese Cancer Association; Nagoya, Japan; Sep. 25-27, 2003].
Ryu, Byungwoo et al.; “Relationship and differentially expressed genes among pancreatic cancers examined by large-scale serial analysis of gene expression”;Cancer Research62:819-826 (Feb. 1, 2002).
Silverman, Jeffrey A. et al.; “Expression of c-myc, c-raf-1, and c-Ki-rasin azaserine-induced pancreatic carcinomas and growing pancreas in rats”;Molecular Carcinogenesis3:379-386 (1990).
Slamon, et al.,Cancer Cells, vol. 7, pp. 371-384 (1989).
Smith, J.P., et al., “Antisense oligonucleotides to gastin inhibit growth of human pancreatic cancer,”Cancer Letters, vol. 135(1), pp. 107-112 (Jan. 8, 1999).
Stein, et al.,Cancer Research, vol. 64, pp. 2805-2816 (Apr. 2004).
Zellner, et al.,Clin. Can. Res., vol. 4, pp. 1797-1802 (1998).
Zhang, Lin et al.; “Gene expression profiels in normal and cancer cells”;Science276:1268-1272 (May 23, 1997).
Zips, et al.,In Vivo, vol. 19, pp. 1-7 (2005).
Database; Biosis Accession No. PREV199191074872; “Expression of c-myc, c-raf-1, and c-Ki-ras in azaserine-induced pancreatic carcinomas and growing pancreas in rats”; 1990.
Database EMBL Nucleotide Sequences [Online], “Agencourt—8303632 NIH—MGC—102Homo sapienscDNA clone Image:6274816 5′, mRNA sequence,” Retrieved from www.ebi.org, Database Accession No. BQ672221 (Aug. 12, 2002).
Database EMBL Nucleotide Sequences [Online], “Agencourt—10154878 NIH—MGC—101Homo sapienscDNA clone Image:6536921 5′, mRNA sequence,” Retrieved from www.ebi.org, Database Accession No. BU527159 (Sep. 16, 2002).
NCBI Sequence View for BI914593, p. 1-2.
NCBI Sequence Viewer for BQ71560, p. 1-2.
NCBI Sequence Viewer for BQ672221, p. 1-2.
Revision History for BI914593, p. 1.
Revision History for BQ71560, p. 1.
Revision History for BQ672221, p. 1.
Sequence Listing; UniProtKB Accession No. Q96GX8; Dec. 1, 2001.
NCBI Sequence Viewer for BQ671560, p. 1-2.
Revision History for BQ671560, p. 1.
Bussenmakers, M., et al., “DD3: A New Prostate-specific Gene, Highly Overexpressed in Prostate Cancer,”Cancer Research, vol. 59(23), pp. 5975-5979 (Dec. 1, 1999).
Ji, P., et al., “MALAT-1, a novel noncoding RNA, and thymosin β4 predict metatasis and survival in early-stage non-small cell lung cancer,”Oncogene, vol. 22(39), pp. 8031-8041 (Sep. 11, 2003).
Schalken, J., et al., “New targets for therapy in prostate cancer: differential display code 3 (DD3PCA3), a highly prostate cancer-specific gene,”Urology, vol. 62(5), Supplement 1, pp. 34-43 (Nov. 2003).
Srikantan, V., et al., “PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer,”PNAS, vol. 97(22), pp. 12216-12221 (Oct. 24, 2000).

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