Genes and markers in type 2 diabetes and obesity

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S091100, C436S063000

Reexamination Certificate

active

07901885

ABSTRACT:
Genes, SNP markers and haplotypes of susceptibility or predisposition to T2D and subdiagnosis of T2D and related medical conditions are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for T2D, obesity and related phenotypes using polymorphisms in the risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of T2D and related traits. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of T2D. Novel methods for prevention and treatment of metabolic diseases such as T2D based on the disclosed T2D genes, polypeptides and related pathways are also disclosed.

REFERENCES:
patent: 6638721 (2003-10-01), Meyers et al.
patent: 6686176 (2004-02-01), Beasley et al.
patent: 2003/0092019 (2003-05-01), Meyer et al.
patent: 2004/0156854 (2004-08-01), Mulligan et al.
patent: WO-02/33056 (2002-04-01), None
patent: WO-2004/006838 (2004-01-01), None
patent: WO-2004/063218 (2004-07-01), None
Ioannidis (Nature Genetics, vol. 29, pp. 306-309, Nov. 2001).
Hirschhorn et al. (Genetics in Medicine. vol. 4, No. 2, pp. 45-61, Mar. 2002).
Barroso et al. (Diabetic Medicine 2005, 22 :517-535).
Mummidi (J Biol Chem, 2002, 275: 18946-18961).
Database SNP (Online), Aug. 20, 2004, “Submitted SNP (ss) Report/ss23763128” retrieved from NCBI. Database accession No. ss23763128.
Database SNP (Online), Jul. 19, 2005, “Submitted SNP (ss) Report/ss44752597” retrieved from NCBI, Database accession No. ss44752597.
Database SNP (Online), Aug. 20, 2004, “Submitted SNP (ss) Report/ss23763076” retrieved from NCBI. Database accession No. 23763076.
Database SNP (Online), Jul. 15, 2005, “Submitted SNO (ss) Report/ss38534782” retrieved from NCBI. Database accession No. ss38534782.
Database SNP (Online), Feb. 12, 2003, “Submitted SNP (ss) Report/ss6743360” retrieved from NCBI. Database accession No. ss6743360.
Prior et al., Diabetologia, Aug. 2005, vol. 48, Supplement 1, p. A143.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Genes and markers in type 2 diabetes and obesity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Genes and markers in type 2 diabetes and obesity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Genes and markers in type 2 diabetes and obesity will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2771880

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.