Genes and genetic elements associated with sensitivity to cispla

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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4351723, 435366, 536 235, 536 241, 536 245, C12Q 168, C12N 1500, C12N 506, C07H 2104

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059423897

ABSTRACT:
The invention provides genetic suppressor elements that confer upon a cell resistance to platinum-based drugs, including cisplatin, methods for identifying and obtaining such elements, and methods of using such elements. The invention also provides cloned genes associated with sensitivity to cisplatin.

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