Generation of human regulatory T cells by bacterial toxins...

Details Generation of human regulatory T cells by bacterial toxins... Generation of human regulatory T cells by bacterial toxins...

2004-04-01

2009-02-24

Ketter, James (Department: 1636)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

C435S320100

Reexamination Certificate

active

07494812

ABSTRACT:
An adoptive immunotherapy using ex vivo-generated regulatory T cells may be used for the suppression of undesireable immune response. T cells are to be obtained from the patient's blood, and upon exposure to a set of toxins from the pathogenA. actinomycetemcomitans, the population of regulatory T cells will be enriched ex vivo and adoptively transferred back to the patient. The novel aspect of the present invention is that it generates large numbers of type 1 regulatory T cells, which secrete Interleukin-10.

REFERENCES:
patent: 5847257 (1998-12-01), Seo et al.
patent: 5958416 (1999-09-01), Birnbaum et al.
patent: 5993803 (1999-11-01), Cohen et al.
patent: 6451316 (2002-09-01), Srivastava
patent: 2006/0177461 (2006-08-01), Young et al.

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