Generation of hematopoietic cells from multipotent neural stem c

Details Generation of hematopoietic cells from multipotent neural stem c Generation of hematopoietic cells from multipotent neural stem c

1998-06-19

2000-07-25

Brusca, John S.

Chemistry: molecular biology and microbiology

Differentiated tissue or organ other than blood, per se, or...

435325, 424 9321, C12N 506

Patent

active

060935316

ABSTRACT:
Multipotent neural stem cell (MNSC) progeny are induced to generate cells of the hematopoietic system by placing the MNSC progeny in a hematopoietic-inducing environment. The hematopoietic-inducing environment can be either ex vivo or in vivo. A mammal's circulatory system provides an in vivo environment that can induce xenogeneic, allogeneic, or autologous MNSC progeny to generate a full complement of hematopoietic cells. Transplantation of MNSC progeny provides an alternative to bone marrow and hematopoietic stem cell transplantation to treat blood-related disorders.

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