Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1989-03-16
1995-01-10
Parr, Margaret
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 435 912, 536 231, 536 235, 536 2431, 536 2433, 536 253, 536 254, 935 8, 935 76, 935 77, 935 78, C12Q 168, C12P 1934, C17H 1700, C12N 1500
Patent
active
053806450
ABSTRACT:
A method is provided for assessing the generalized genetic change which occurs during tumorigenesis. The method relies on measurement of loss of a large number of alleles from the chromosomes of the tumor cells. The alleles are RFLP markers. The role of any of the particular alleles in tumorigenesis need not be known. The amount of allelic loss allows a prognosis to be made regarding tumor metastasis, tumor recurrence, and mortality.
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Parr Margaret
Sisson Bradley L.
The Johns Hopkins University
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