Patent
1997-09-12
1999-06-29
Teska, Kevin J.
G06G 748
Patent
active
059180382
ABSTRACT:
A method for obtaining the profile area and volume of any specified section of any specified corpuscle is disclosed. The operator operates a personal computer running a program which includes a general representation of the corpuscle to be sectioned. The operator specifies two coordinate rotation angles and two section positions, as well as additional attributes of the corpuscle representation, in response to prompts on a video screen, using a keyboard. The program superimposes a unit cubic lattice on the corpuscle representation. Two coordinate rotations are performed defining a new X'-Y' plane, and two sectioning planes are drawn parallel to a new X'-Y' plane. The new X'-Y' plane is subdivided into unit squares. The program then examines each lattice point in turn. The volume of the corpuscle section is obtained by counting the total number of those lattice points which lie in the interior of the corpuscle between the sectioning planes; the profile area of the corpuscle section is obtained by counting the total number of unit squares which contain the orthogonal projection of at least one of those lattice points.
REFERENCES:
patent: 5477334 (1995-12-01), Keswani et al.
McCready RW, Papadimitriou J M. An Analysis of DNA cytomorphometry on tissue sections in a rat liver model. Analytical and Quantitative Cytology 5:117-123, 1983.
Nikonenko AG. The cell sectioning model: Nuclear/cytoplasmic ratio studied by computer simulation. Analytical and Quantitative Cytology and Histology 18: 23-34, 1996.
Baba, N: Computer-aided three-dimensional reconstruction from serial section images. In Hader DP ed. Image Analysis in Biology, CRC Press, pp. 251-270, 1991.
Gundersen et al.: Stereological estimation of the volume-weighted mean volume of arbitrary particles observed on random section, J. Microsc. vol. 138; pp. 127-142, 1985.
Cruz-Orive et al.: Recent Stereological methods for cell biology: a brief survey, Am. J. Physiol., vol. 258; pp. L148-L156, 1990.
Kubinova: Advantages of sterological methods in biomedicine. Efficiently obtaining unbiased estimates of geometrical charactertics for 3-D structures, IEEE Engineering in Medicine and Biology Magazine, vol. 17; pp. 110-115, 1998.
Jones Hugh
Teska Kevin J.
LandOfFree
General method for determining the volume and profile area of a does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with General method for determining the volume and profile area of a , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and General method for determining the volume and profile area of a will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1385118