Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1994-11-18
1997-03-25
Guzo, David
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4353201, 536 241, 514 44, C12N 1563, C12N 1585, C07H 2104
Patent
active
056143982
ABSTRACT:
DNA recombination can be effected through transposition by injecting a host with a transposition vector prepared from the terminal sequences of the Hermes element of M. domestica on either side of a structural gene to be expressed in the recombinant host. Transposition can be improved by use of a helper plasmid including the transposase gene of Hermes operably linked to a promoter sequence effective in the host.
REFERENCES:
Marshall, "Gene Therapy's Growing Pains", Science, vol. 269, 25 Aug. 1995, pp. 1050-1055.
Atkinson Peter
O'Brochta David
Warren William
Guzo David
The University of Maryland Biotechnology Institute
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