Gene therapy using stromal cells

Details Gene therapy using stromal cells Gene therapy using stromal cells

1997-08-19

1999-11-30

Stanton, Brian R.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 931, 424 932, 514 44, A01N 6300

Patent

active

059938013

ABSTRACT:
A method of causing production and secretion into the bloodstream of a human patient of a biologically active enzyme for which the human patient suffers a deficiency; the method involves introducing into the human patient donor bone marrow stromal cells which have been transfected with a gene encoding the enzyme, so that the introduced cells can adhere to a bone cavity surface of the patient and produce and secrete the active enzyme.

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