Gene therapy using stromal cells

Details Gene therapy using stromal cells Gene therapy using stromal cells

1995-03-22

1998-12-15

Stone, Jacqueline M.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

4353201, 4352402, A61K 4800, C12N 510

Patent

active

058492879

ABSTRACT:
A method of causing production and secretion into the bloodsream of a human patient of a biologically active enzyme for which the human patient suffers a deficiency; the method involves introducing into the human patient donor bone marrow stromal cells which have been transfected with a gene encoding the enzyme, so that the introduced cells can adhere to a bone cavity surface of the patient and produce and secrete the active enzyme.

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