Gene targeting vectors comprising conditional positive...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S091400, C435S455000, C435S440000, C435S325000, C435S069100, C435S029000, C435S320100, C536S023100

Reexamination Certificate

active

06929909

ABSTRACT:
The present invention is directed to methods and compositions useful in producing cells and animals having a disruption or modification of a target gene. Vectors useful in producing these cells and animals are described. In addition, methods of screening and enriching cells comprising a targeted gene modification are provided.

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