Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Patent
1994-08-22
1998-01-13
Patterson, Jr., Charles L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
435220, 43525233, 4353201, 536 232, 536 2432, C12Q 134, C12N 952, C12N 1557
Patent
active
057078220
ABSTRACT:
Methods and compositions are provided for cloning and expression of serum opacity factor of Streptococcus pyogenes genes. The portion produced by the recombinant DNA techniques described herein may be employed in qualitative and quantitative testing for high density lipoprotein, as a fibronectin binding factor and for the regulation of high density lipoprotein in a mammal. The gene may further be employed as a molecular probe for accurate identification of opacity factors from various strains of Streptococcus pyogenes.
REFERENCES:
Martinez, O.V. et al., (1978) J. Gen. Microbiol. 105, 29-38.
Saravani, G.A. et al., (1990) FEMS Microbiol. Letts. 68, 35-40.
Lee, C.C., et al., (1988) Science 239, 1289-1291.
Young, R.A., et al., (1983) Science 222, 778-782.
Fischetti Vincent A.
Rakonjac Jasna
Robbins John
Patterson Jr. Charles L.
The Rockefeller University
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