Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1998-12-14
2000-06-06
Achutamurthy, Ponnathapu
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530300, 435 691, 43525233, 4353201, 536 235, C07K 100, A61K 3800
Patent
active
060720344
ABSTRACT:
The present invention relates, in general, to a cancer-related protein and to a nucleic acid sequence encoding same. In particular, the invention relates to a protein over expressed in certain neoplastic cells, including breast and ovarian cancer cells, to its encoding sequence, and to diagnostic and treatment methodologies based on same.
REFERENCES:
patent: 5589358 (1996-12-01), Dawson
Lee, "The Accumulation of Three Specific Proteins Related to Glucose-Regulated Proteins in a Temperature-Sensitive Hamster Mutant Cell Line K12", Journal of Cellular Physiology 106:119-125 (1981).
Cole et al, "Cloning and Expression in Escherichia coli K-12 of the Genes for Major Outer Membrane Protein OmpA from Shigella dysenteriae, Enterobacter aerogenes, and Serratia marcescens", Journal of Bacteriology 149(1):145-150 (1982).
Kaufman Russel E.
Slentz-Kesler Kimberly
Achutamurthy Ponnathapu
Duke University
Nashed Nashaat T.
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