Gene product over expressed in cancer cells

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435325, 4352523, 43525213, 4353201, 530350, 536 235, 536 231, C12P 2106, C07H 2104

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059121424

ABSTRACT:
The present invention relates, in general, to a cancer-related protein and to a nucleic acid sequence encoding same. In particular, the invention relates to a protein over expressed in certain neoplastic cells, including breast and ovarian cancer cells, to its encoding sequence, and to diagnostic and treatment methodologies based on same.

REFERENCES:
patent: 5589358 (1996-12-01), Dawson
Lee, A. S. Accumulation of three specific proteins related to glucose-regulated proteins in a Temperature sensitive hamster mutant cell line K12 J. Cellu. Physiol. 106, 119-125, Jan. 1981.
Cole et al, "Cloning and Expression in Escherichia coli K-12 of the Genes for Major Outer Membrane Protein OmpA from Shigella dysenteriae, Enterobacter aerogenes, and Serratia marcescens", Journal of Bacteriology 149(1):145-150 (1982).

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