Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1988-12-02
1991-11-19
Wax, Robert A.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 6, 435 91, 4351723, 436501, 436813, 935 4, 935 78, C07H 2104, C12Q 168
Patent
active
050667920
ABSTRACT:
Gene probes containing genetic sequences that code for proteins which are phenotypically characteristic of certain leukemias, such as chronic myelogenous leukemia, can be prepared from RNA of a person having that disease. A useful probe has been found which comprises a sequence localized to chromosome 8, the sequence being complementary to a mRNA that is characteristically present in high abundance in chronic myelogenous leukemia cells. The gene probes can be used in diagnostic hybridization tests with RNA or a patient to be diagnosed.
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Mars Wendy M.
Saunders Grady F.
Board of Regents University of Texas
Marschel Ardin H.
Wax Robert A.
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