Gene participating in the production of homo-glutamic acid...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

Reexamination Certificate

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C435S183000, C435S252300, C435S252330, C435S320100, C536S023100, C536S023200

Reexamination Certificate

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06890746

ABSTRACT:
Provided are an isolated gene capable of participating in the production of L-homoglutamic acid, and a production system of L-homoglutamic acid by using this gene. The gene is derived from the genome ofFlavobacterium lutescens.

REFERENCES:
patent: 9631616 (1996-10-01), None
Attwood et al. Which craft is best in bioinformatics? Comput. Chem. 2001, vol. 25(4), pp. 329-339.*
Ponting, C.P. Issues in predicting protein function from sequence. Brief. Bioinform. Mar. 2001, vol. 2(1), pp. 19-29.*
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T. Yagi et al., “A Novel Purification Procedure of L-Lysine 6-Aminotransferase from Flavobacterium Lutescence”, Biochem., Biophys. Acta. (1980), vol. 614, No. 1, pp. 63-70.
J.R. Coque et al., “A Gene Encoding Lysine 6-Aminotransferase, Which Forms the β-Lactam Precursor α-Aminoadipic Acid, is Located in the Cluster of Cephamycin Biosynthetic Genes in Nocardia Lactamdurans”, J. Bioteriol. (1991), vol. 173, No. 19, pp. 6258-6264.
K. Madduri et al., “Cloning of Location of a Gene Governing Lysine ε-Aminotransferase, an Enzyme Initialing β-Lactum Biosysthesis in Streptomyces spp.”, J. Bioteriol. (1991), vol. 173, pp. 985-988.
J.F. Martin et al., “Genes for β-Lactum Antibiotic Biosynthesis”, Antonie van Leeuwenhoek (1995), vol. 181, No. 2, pp. 181-200.
A.L. Leitao et al., “Inducing Effect of Diamines on Transcription of the Cephamycin C Genes from the lat and pcbAB Promoters in Nocardia Lactamdurans” J. Bacteriol. (Apr. 1999,), vol. 181, No. 8, pp. 2379-2384.
J.P. Francisco et al., “The pcd Gene Encoding Piperideine-6-Carboxylate dehydrogenase Involved in Biosynthesis of α-Aminoadipic Acid is Located in the Cephamycin Cluster of Streptomyces Clavuligerus”, J. Bacteriol. (Sep. 1998,) vol. 180, No. 17, pp. 4753-4756.
L.F. Juan et al., “Δ-1-Piperideine-6-carboxylate dehydrogenease, a new enzyme that forms α-aminoadipate inStreptomyces clavuligerusand other cephamycin c-producing actinomycetes”, Biochem. J. (1997), vol. 327, No. 1, pp. 59-64.

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