Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi
Patent
1987-01-05
1992-03-17
Martinell, James
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Fungi
435 694, 4351723, 43525233, 435256, 4353201, 536 27, 935 13, 935 28, 935 69, 935 73, C12N 1518, C12N 1570, C12N 1563, C12N 116, C12N 118
Patent
active
050968254
ABSTRACT:
A DNA having a base sequence coding for human epidermal growth factor has been synthesized in blocks, and cloned. Novel recombinant DNA transfer vectors containing said cloned DNA have been constructed. The codon usage of the sequence reflects the codon bias of yeast. The DNA sequence is useful for the large scale synthesis of human epidermal growth factor in yeast cells or microorganisms transformed by said recombinant DNA transfer vectors.
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Barr Philip J.
Merryweather James P.
Mullenbach Guy T.
Urdea Mickey S.
Valenzuela Pablo
Chiron Corporation
Martinell James
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