Gene for ataxia-telangiectasia complementation group D (ATDC)

Details Gene for ataxia-telangiectasia complementation group D (ATDC) Gene for ataxia-telangiectasia complementation group D (ATDC)

1992-06-22

1995-03-07

Draper, Garnette D.

Chemistry: molecular biology and microbiology

Vector, per se

435 691, 4352401, 536 231, 536 243, C12N 1500, C07H 2104

Patent

active

053957679

ABSTRACT:
Disclosed herein is a new gene, an AT gene for complementation group D, the ATDC gene and fragments thereof. Nucleic acid probes for said gene are provided as well as proteins encoded by said gene, cDNA therefrom, preferably a 3 kilobase (kb) cDNA, and recombinant nucleic acid molecules for expression of said proteins. Further disclosed are methods to detect mutations in said gene, preferably methods employing the polymerase chain reaction (PCR). Also disclosed are methods to detect AT genes from other AT complementation groups.

REFERENCES:
Jacobs et al., 1985, Nature, vol. 313, pp. 806-810.
Foroud et al., Am. J. Hum. Genet., 49: 1263-1279 (1991).
Kapp and Painter, Int. J. Radiat. Biol., 56 (5): 667-675 (1989).
Lambert et al., PNAS (USA), 88: 5907-5911 (Jul. 1991).
McConville et al., Nucleic Acids Research, 18 (15): 4335-4343.

Affiliated with

Also associated with

Rating

Gene for ataxia-telangiectasia complementation group D (ATDC) does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gene for ataxia-telangiectasia complementation group D (ATDC), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gene for ataxia-telangiectasia complementation group D (ATDC) will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1405611